The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 1998
Filed:
Apr. 05, 1995
Andrew Reginald Clark, Half Moon Bay, CA (US);
Chung C Hsu, Los Altos, CA (US);
Andrew J Walsh, San Francisco, CA (US);
Genentech, Inc., So. San Francisco, CA (US);
Abstract
Disclosed herein is a method for the preparation of sodium chloride formulations having a substantially uniform particle size suitable to ensure the dispersible properties for inhalation into the lungs of a subject. The formulations thus prepared are also the subject of this disclosure. The method involves jet milling coarse sodium chloride in one or preferably two or more procedures using air pressure suitable to produce particles having a significant fraction that are less than about 7 microns in size. Immediately following the milling, the particles are vacuum dried in an oven using a temperature and time suitable to cure the product to prevent substantial aggregation over time.