The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 1998

Filed:

Dec. 26, 1995
Applicant:
Inventors:

Ronald R Price, Stevensville, MD (US);

Mariam Monshipouri, Bethesda, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; A23L / ; B01J / ;
U.S. Cl.
CPC ...
435178 ; 264-43 ; 264-432 ; 264-47 ; 426534 ; 426573 ; 4352625 ; 435821 ;
Abstract

Microspheres, of controllable shape and size, encapsulating active ingredients, are made by the internally controlled gelation of an emulsion including a water-soluble polysaccharide, a salt of a di- or trivalent metal cation, a polymerization inhibitor, water, a water-immiscible solvent (as a non-aqueous phase), and the active ingredient. The components of the aqueous phase, containing the water-soluble polysaccharide, polymerization inhibitor, di- or trivalent metal salt, active substance, and water, are blended together. This aqueous phase is then gradually mixed with the oil phase and agitated to form an emulsion. After sufficient time for solidification, the emulsion is broken and the resulting microspheres are collected. The active ingredient may be various substances, including live microorganisms.


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