The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 1998

Filed:

Apr. 07, 1994
Applicant:
Inventors:

Enzo Paoletti, Delmar, NY (US);

Steven Elliot Pincus, East Greenbush, NY (US);

Assignee:

Virgenetics Corporation, Troy, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C12N / ;
U.S. Cl.
CPC ...
4241991 ; 4352351 ; 4353201 ; 4242181 ; 4241861 ; 4242321 ;
Abstract

What is described is a recombinant poxvirus, such as vaccinia virus, fowlpox virus and canarypox virus, containing foreign DNA from flavivirus, such as Japanese encephalitis virus, yellow fever virus and Dengue virus. In a preferred embodiment, the recombinant poxvirus generates an extracellular particle containing flavivirus E and M proteins capable of inducing neutralizing antibodies, hemagglutination-inhibiting antibodies and protective immunity against flavivirus infection. What is also described is a vaccine containing the recombinant poxvirus for inducing an immunological response in a host animal inoculated with the vaccine.


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