The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 1998
Filed:
Jan. 19, 1996
Yasmin Thanavala, Williamsville, NY (US);
Arvind Thakur, Williamsville, NY (US);
Ivan Roitt, Golders Green, GB;
Michael Pride, Houston, TX (US);
Health Research, Inc., Buffalo, NY (US);
University College London, London, GB;
Abstract
The invention comprises an anti-idiotypic antibody designated 2F10 and permitted variants thereof, which have antigenic properties similar to the group specific 'a' determinant of human hepatitis B surface antigen HBsAg and have at least partial but not complete homology with such surface antigen. The invention further comprises a peptide having a chain comprising the amino acid residues Ala Val Tyr Tyr Cys Thr Arg Gly Tyr His Gly Ser Ser Leu Tyr and permitted variants thereof, which, like 2F10, have antigenic properties similar to the group specific 'a' determinant of human hepatitis B surface antigen HBsAg and have at least partial, but not complete, homology with said surface antigen. The amino acid sequence is found in and forms a part of 2F10. The shorter peptide chain comprising the amino acid residues Gly Tyr His Gly Ser Ser Leu Tyr and permitted variants thereof, also have antigenic properties similar to the group specific 'a' determinant of human hepatitis B surface antigen HBsAg and have at least partial, but not complete, homology with said surface antigen.