The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 1998

Filed:

Sep. 22, 1995
Applicant:
Inventors:

Mahmood Rezazadeh Azari, Gurnee, IL (US);

August A Ebeling, Palatine, IL (US);

John E Picken, Village of Lakewood, IL (US);

Timothy N Estep, Grayslake, IL (US);

Assignee:

Baxter International, Inc., Deerfield, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ;
U.S. Cl.
CPC ...
530385 ; 514-6 ;
Abstract

During the purification of pharmaceutical grade crosslinked hemoglobin mixtures of crosslinked and uncrosslinked hemoglobin are heated in the presence of nonstoichiometric amounts of oxygen, resulting in the selective precipitation of the uncrosslinked hemoglobin. After separation of the precipitated uncrosslinked tetramers, the crosslinked hemoglobin remaining in the supernatant is so purified that a further chromatography purification step is unnecessary. This hemoglobin is highly crosslinked absolutely free of chromatography fines, and has a low methemoglobin content.


Find Patent Forward Citations

Azari, Mahmood. (1998). Preparation of pharmaceutical grade hemoglobins by heat treatment in (U.S. Patent No. 5741894). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5741894

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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