The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 1998

Filed:

Jun. 13, 1994
Applicant:
Inventors:

Gregory R Reyes, Palo Alto, CA (US);

Daniel W Bradley, Lawrenceville, GA (US);

Jr-Shin Twu, Daly City, CA (US);

Michael A Purdy, Atlanta, GA (US);

Albert W Tam, San Francisco, CA (US);

Krzysztof Z Krawczynski, Tucker, GA (US);

Patrice D Yarbough, San Antonio, TX (US);

Assignee:

Genelabs Technologies, Inc., Redwood City, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
4241891 ; 4241921 ; 4241931 ; 4242281 ; 4242181 ; 935 65 ;
Abstract

Antigen and antibody vaccine composition effective in preventing hepatitis E virus (HEV) infection are disclosed. The antigen composition includes a peptide corresponding to a carboxyl terminal end region of the capsid protein encoded by the second open reading frame 2 of the HEV genome. The composition is effective in preventing HEV infection after vaccination. The antibody composition contains an antibody effective to block HEV infection of human primary hepatocytes in culture.


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