The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 1998
Filed:
May. 31, 1995
Applicant:
Inventors:
Barrett Rollins, Brookline, MA (US);
Yujun Zhang, Brookline, MA (US);
Assignee:
Dana-Farber Cancer Institute, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C08H / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514-8 ; 424 851 ; 514 12 ; 514 21 ; 530351 ; 530395 ; 530402 ; 530409 ;
Abstract
The invention relates to mutant chemokines and pharmaceutical compositions thereof, wherein the mutant inhibits the corresponding endogenous chemokine from binding or activating a responsive receptor. The claimed mutant chemokines can be administered to a patient for the treatment or prophylaxis of a chemokine-mediated disease. The invention further relates to isolated DNAs encoding the mutant chemokines, vectors and recombinant host cells containing the same.