The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 1998

Filed:

Feb. 20, 1997
Applicant:
Inventors:

Robert C Gadwood, Kalamazoo, MI (US);

Michael Robert Barbachyn, Kalamazoo, MI (US);

Dana Scott Toops, Kalamazoo, MI (US);

Herman Walden Smith, Kalamazoo, MI (US);

Valerie Ann Vaillancourt, Kalamazoo, MI (US);

Assignee:

Pharmacia & Upjohn Company, Kalamazoo, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514252 ; 514254 ; 544368 ; 544369 ;
Abstract

Compounds useful in the preparation of pharmaceutical preparations for the treatment of microbial infection where such compounds are of structural Formula I ##STR1## or pharmaceutically acceptable salts thereof wherein: R.sup.1 is --CHO, --COCH.sub.3, --COCHCl.sub.2, --COCHF.sub.2, --CO.sub.2 CH.sub.3, --SO.sub.2 CH.sub.3, or --COCH.sub.2 OH; X.sup.1 and X.sup.2 are independently H, F, or Cl; and Q is a five membered ting heterocycle (azolyl ring) of the general form: ##STR2## wherein A, B, and C are independently oxygen (O), nitrogen (N), sulfur (S) or Carbon (C). In all cases, the piperazine nitrogen atom is attached at the carbon atom of the carbon-nitrogen double bond.


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