The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 1998
Filed:
Jun. 07, 1995
Applicant:
Inventors:
Lars Abrahmsen, Stockholm, SE;
John Burnier, Pacifica, CA (US);
James A Wells, Burlingame, CA (US);
David T Jackson, San Mateo, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C12P / ; C07K / ;
U.S. Cl.
CPC ...
514 12 ; 435 681 ; 435212 ; 435213 ; 435214 ; 435215 ; 435216 ; 435217 ; 435218 ; 435219 ; 435220 ; 435221 ; 435222 ; 435223 ; 435224 ; 435225 ; 435226 ; 530338 ; 530345 ; 530409 ; 530410 ;
Abstract
The invention relates to serine protease variants derived from precursor serine proteases via recombinant and/or chemical methods to form protease variants having improved peptide ligase activity. The invention also includes novel ligation substrates which in combination with the serine protease variants and a second ligation substrate are capable of forming a ligation product. The invention also relates to methods for forming such ligation products and the products formed thereby.