The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 1998
Filed:
Sep. 27, 1996
Applicant:
Inventors:
Frank Grenier, Libertyville, IL (US);
Thomas F Holzman, Libertyville, IL (US);
Allan H Smith, Zion, IL (US);
Alan C Tsurutani, Chicago, IL (US);
Assignee:
Abbott Laboratories, Abbott Park, IL (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; C07K / ;
U.S. Cl.
CPC ...
436-8 ; 436 10 ; 436 11 ; 436 16 ; 436 17 ; 436 18 ; 436501 ; 530350 ;
Abstract
The present invention is directed to an in vitro aqueous composition comprising a drug, preferably tacrolimus or rapamycin, having enhanced stability. The invention utilizes a binding protein, preferably FKBP, to stabilize the drug in an aqueous matrix.