The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 1998

Filed:

Sep. 05, 1996
Applicant:
Inventors:

Vladimir A Stoy, Princeton, NJ (US);

Charles K Kliment, Princeton, NJ (US);

Assignee:

Hymedix International, Inc., Dayton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
424 7802 ; 424 7804 ; 424 7817 ; 424 7835 ; 5147726 ;
Abstract

The present invention is directed to a composition comprising a nitrogen-containig drug-polymer salt and a method for making said composition. The drug-polymer salt is comprised of one or more drugs having basic groups as part of their chemical structure which are capable of forming salts with acids and one or more hydrophilic polymers containing carboxylate groups and amidine groups as pendant groups. Such polymeric salts of drugs have been found to have excellent bio-availability and advantageous release profiles in various forms (gels, ointments, pills, etc.). Particularly advantageous polymers contain pendant nitrile groups in addition to carboxyls and amidines which provide the polymer with hydrogel characteristics.


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