The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 1998
Filed:
Oct. 31, 1995
Applicant:
Inventors:
Muzammil M Mansuri, Lexington, MA (US);
Krishna K Murthi, Waltham, MA (US);
Kollol Pal, Needham, MA (US);
Assignee:
Mitotix, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514337 ; 514254 ; 514256 ; 514274 ; 514312 ; 514320 ; 514324 ; 514432 ; 514456 ; 544238 ; 544315 ; 544318 ; 544408 ; 546153 ; 546196 ; 5462831 ; 549 23 ; 549401 ; 549403 ;
Abstract
The invention provides novel inhibitors of cyclin-dependent kinases, in particular inhibitors of the CDK/cyclin complexes such as CDK4/cyclin D1. The novel compounds are analogs of chromones. These compounds can be used for inhibiting excessive or abnormal cell proliferation. Thus, the novel compounds are useful for treating a subject with a disorder associated with excessive cell proliferation, such as cancer.