The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 1998
Filed:
Jun. 07, 1995
Applicant:
Inventor:
Judy S Riffle, Blacksburg, VA (US);
Assignee:
Thoratec Laboratories, Inc., Berkeley, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ; A61K / ; A61K / ; C08H / ; C08L / ; C08L / ; C08L / ; C08L / ; C08L / ; C08G / ; C07K / ; C07K / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
424 7808 ; 424 7817 ; 424 7818 ; 424 7827 ; 424 7831 ; 424 7835 ; 424 7837 ; 514-2 ; 524 17 ; 524 20 ; 524188 ; 524261 ; 524262 ; 524265 ; 524267 ; 524269 ; 524498 ; 524499 ; 524506 ; 524507 ; 524515 ; 524577 ; 524588 ; 524589 ; 524590 ; 525541 ; 525 5411 ; 525 88 ; 525 90 ; 525 / ; 525 / ; 525 / ; 525 / ; 525 96 ; 525 95 ; 525100 ; 525101 ; 525102 ; 525106 ; 525123 ; 525130 ; 525217 ; 525231 ; 525241 ; 525452 ; 525453 ; 525455 ; 525457 ; 5262381 ; 526279 ; 526346 ; 528 10 ; 528 44 ; 528 25 ; 528 28 ; 528 85 ; 527200 ; 527201 ; 527203 ; 527204 ; 530300 ; 530345 ;
Abstract
A hemocompatible surface-modifying additive is provided for modifying polyurethane or polyurethane urea substrates. The additive has a polyurethane or polyurethane urea hard block or an alternative block which is miscible with the poly(urethane) or poly(urethane-urea) base polymer, a polysiloxane hydrophobic soft block, an optional hydrophilic spacer and a peptide selected from the group consisting of Arg-Gly-Asp, X-Arg-Gly-Asp, Arg-Gly-Asp-X and X-Arg-Gly-Asp-X', wherein X and X' are amino acids.