The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 1998
Filed:
Oct. 24, 1995
Applicant:
Inventors:
Peter R Bernstein, Wallingford, PA (US);
Scott C Miller, Hamden, CT (US);
Assignee:
Zeneca Limited, London, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
5142278 ; 5142355 ; 5142358 ; 514252 ; 514255 ; 514315 ; 514316 ; 514318 ; 514320 ; 514329 ; 514341 ; 514342 ; 514343 ; 544 581 ; 544 59 ; 544162 ; 544358 ; 544360 ; 544382 ; 544386 ; 546193 ; 546194 ; 546195 ; 546196 ; 546197 ; 546198 ; 546199 ; 546200 ;
Abstract
Compounds of formula I ##STR1## wherein Q.sup.1, Q.sup.2, Q.sup.3, and Q.sup.4 have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists of SP and NKA are useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.