The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 1998
Filed:
Aug. 08, 1995
Applicant:
Inventors:
David Askin, Warren, NJ (US);
Kan K Eng, Jersey City, NJ (US);
Peter E Maligres, Scotch Plains, NJ (US);
Paul J Reider, Westfield, NJ (US);
Kai Rossen, Westfield, NJ (US);
Ralph P Volante, Cranbury, NJ (US);
Veena Upadhyay, Edison, NJ (US);
Steven A Weissman, Little Falls, NJ (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
548217 ;
Abstract
A process for synthesizing the epoxide of the formula ##STR1## consists of, at a minimum, formation of a halohydrin from the allyl acetonide reactat, followed by base-induced cyclization, the epoxide product I being useful as an intermediate for the synthesis of inhibitors of renin or HIV protease or other proteases.