The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 1998

Filed:

May. 12, 1995
Applicant:
Inventors:

Ronald W Barrett, Sunnyvale, CA (US);

Steven E Cwirla, Menlo Park, CA (US);

William J Dower, Menlo Park, CA (US);

Kerry J Koller, San Francisco, CA (US);

Jung Lee, Mountain View, CA (US);

Christine L Martens, Portola Valley, CA (US);

Beatrice Ruhland, Los Altos, CA (US);

Assignee:

Affymax Technologies N.V., Greenford, GB;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
530324 ; 530327 ; 530328 ; 530329 ; 530330 ; 530331 ; 514 12 ; 514 15 ; 514 17 ; 514 18 ;
Abstract

Disclosed are peptides and peptide mimetics that bind selectins, including endothelial leukocyte adhesion molecule 1 (ELAM-1). Such peptides and peptide mimetics are useful in methods for blocking adhesion of leukocytes to the selectins for the purpose of inhibiting inflammation as well as in diagnostic methods employing labeled peptides and peptide mimetics that bind selectins for the purpose of determining the site of inflammation in mammals which inflammation is mediated by the presence of one or more selectins.


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