The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 1998

Filed:

Jun. 07, 1995
Applicant:
Inventors:

Markku Jalkanen, FIN-20760 Piispanristi, FI;

Leena Alanen-Kurki, Fin-20500 Turku, FI;

Petri Auvinen, 69126 Heidelberg, DE;

Panu Jaakkola, FIN 20500 Turku, FI;

Sirpa Leppa, Fin 20660 Littoinen, FI;

Markku Mali, FIN-24280 Salo, FI;

Tapani Vihinen, FIN 20700, FI;

Anni Warri, 21420 Lieto, FI;

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C07H / ;
U.S. Cl.
CPC ...
435354 ; 4353201 ; 536 241 ;
Abstract

Methods are provided for altering levels of syndecan within a cell. The methods include enhancing syndecan expression via administration of growth factors, preventing suppression of syndecan expression via administration of anti-steroid agents, and altering syndecan biochemistry within the cell. The methods are used to induce or maintain cellular differentiation, and to decrease the growth of malignant cells. Application of the methods to the treatment of patients, including humans, is provided.


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