The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 10, 1998
Filed:
Mar. 08, 1996
Applicant:
Inventor:
Jerrold M Olefsky, Solana Beach, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ;
U.S. Cl.
CPC ...
435-721 ; 435-78 ; 436501 ;
Abstract
A screening method for identifying compositions which affect the binding of protein tyrosine phosphatase 1B (PTP1B) to phosphorylated insulin receptor is provided. This method measures a composition's ability to inhibit binding of PTP1B to the .beta.-subunit of the insulin receptor rather than phosphatase activity in general. Also provided are specific phosphopeptides which affect the binding of protein tyrosine phosphatase 1B (PTP1B) to phosphorylated insulin receptor.