The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 1998
Filed:
Jun. 13, 1996
Applicant:
Inventors:
Michael R Jirousek, Indianapolis, IN (US);
William Francis Heath, Jr, Fishers, IN (US);
Douglas Kirk Ways, Indianapolis, IN (US);
Lawrence E Stramm, Indianapolis, IN (US);
Assignee:
Eli Lilly & Company, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514183 ; 514410 ; 514450 ; 514459 ; 540470 ; 540467 ; 540472 ; 540474 ;
Abstract
A method for treating endothelial cell dysfunction, such as associated with cardiovascular disease are disclosed, particularly using the isozyme selective PKC inhibitor, (S)-3,4-�N,N'-1,1'-((27'-ethoxy)-3''(O)-4''-(N,N-dimethylamino)-butane)-bi s-(3,3'-indolyl)!-1(H)-pyrrole-2,5-dione hydrochloride salt.