The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 1998
Filed:
Oct. 28, 1996
John J Acton, III, Cranford, NJ (US);
Alan D Adams, Cranford, NJ (US);
Jeffrey D Hermes, Warren, NJ (US);
A Brian Jones, Scotch Plains, NJ (US);
William Hugh Parsons, Belle Mead, NJ (US);
Peter J Sinclair, Highland Park, NJ (US);
Merck & Co., Inc., Rahway, NJ (US);
Abstract
Compounds of the formula ##STR1## are inhibitors of peptide binding to major histocompatibility complex type II proteins and are useful in the treatment and prevention of autoimmune diseases including: rheumatoid arthritis, Type I diabetes, multiple sclerosis, lupus erythematosis, Graves disease and pemphigus. The present invention also provides novel compositions, methods of treatment employing the compounds of the present invention and methods of manufacture of the compounds of structural formula (I).