The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 1998
Filed:
Apr. 02, 1996
Applicant:
Inventors:
Chengxi Yang, Glenview, IL (US);
Hemantkumar H Patel, Waukegan, IL (US);
Yi-Yin Ku, Buffalo Grove, IL (US);
Jih-Hua Liu, Green Oaks, IL (US);
Assignee:
Abbott Laboratories, Abbott Park, IL (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C07H / ;
U.S. Cl.
CPC ...
536-74 ; 536-72 ; 536 185 ; 536 186 ;
Abstract
A process of preparing a 6-O-methyl erythromycin A derivative using a 2'-protected, 9-etheroxime erythromycin A intermediate is provided. A preferred protecting group for the 2'-position is acetyl. 2'-protected, 9-etheroxime erythromycin A derivatives are also provided. Also disclosed is a method for inhibiting quaternary salt formation at the 3' amine without the need for 3'N-protecting groups.