The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 1998
Filed:
Jul. 10, 1995
Applicant:
Inventors:
M Brian Arnold, Bargersville, IN (US);
Thomas J Bleisch, Indianapolis, IN (US);
David R Helton, Greenfield, IN (US);
Mary Jeanne Kallman, Greenfield, IN (US);
Paul L Ornstein, Carmel, IN (US);
Darryle D Schoepp, Indianapolis, IN (US);
Joseph P Tizzano, New Palestine, IN (US);
Assignee:
Eli Lilly and Company, Lilly Corporate Center, IN (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07C / ; C07D / ; C07D / ; C07D / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
548511 ; 514454 ; 514461 ; 514514 ; 514531 ; 514538 ; 514566 ; 5483191 ; 549 72 ; 549390 ; 560 20 ; 560 36 ; 560 45 ; 560 46 ; 560 47 ; 562433 ; 562435 ; 562441 ; 562442 ; 562444 ; 562451 ; 562456 ; 562458 ;
Abstract
The present invention provides compounds of formula ##STR1## in which R represents an organic group, or a pharmaceutically acceptable metabolically labile ester or amide thereof, or a pharmaceutically acceptable salt thereof, which are useful as antagonists of one or more of the actions of L-glutamate at metabotropic excitatory amino acid receptors.