The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 10, 1998

Filed:

Sep. 09, 1996
Applicant:
Inventors:

Kenneth D Bagshawe, London, GB;

Michael Jarman, Sutton, GB;

Caroline Joy Springer, London, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
514517 ; 514562 ; 514563 ; 558 44 ; 558 47 ; 558 52 ; 558 53 ; 558 54 ; 564138 ;
Abstract

Nitrogen mustard pro-drugs of the formula ##STR1## are disclosed where R is the residue of an .alpha.-amino acid RNH.sub.2 and M is a disubstituted amino 'mustard' group, useful in antibody directed enzyme pro-drug therapy in the treatment of cancer.


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