The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 1998
Filed:
Apr. 20, 1995
Applicant:
Inventors:
Leonid Beigelman, Longmont, CO (US);
Alex Karpeisky, Boulder, CO (US);
Assignee:
Ribozyme Pharmaceuticals, Inc., Boulder, CO (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12Q / ; A61K / ; C07H / ;
U.S. Cl.
CPC ...
4352401 ; 435-6 ; 435 912 ; 514 44 ; 536 245 ; 536 221 ; 536 231 ; 536 243 ; 536 2431 ; 536 2433 ; 536 251 ;
Abstract
A compound having the formula: ##STR1## wherein, R1 represents 2'-O-R.sub.3 -thio-R.sub.3 and/or 2'-C-R.sub.3 -thio-R.sub.3, wherein R.sub.3 is independently a moiety selected from a group consisting of alkyl, alkenyl, alkynyl, aryl, alkylaryl, carbocyclic aryl, heterocyclic aryl, amide and ester, X represents a base or H; Y represents a phosphorus-containing group; and R2 represents H, DMT or a phosphorus-containing group.