The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 10, 1998

Filed:

Jan. 29, 1996
Applicant:
Inventors:

Brian S Bull, Loma Linda, CA (US);

Ralph A Korpman, Redlands, CA (US);

Assignee:

Medical Devices Corporation, San Bernardino, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; B05D / ;
U.S. Cl.
CPC ...
435 13 ; 427212 ;
Abstract

A method for optically measuring the functional capacity of blood platelets and the blood clotting system. The method consists of detection of platelet aggregation in a platelet-containing specimen fluid, whereby the specimen fluid is contacted with a platelet agonist and disclosure reagent. A mechanical specimen-handling apparatus with one or more optical end-point detectors which is preferred for use with the method of the invention is also described. The apparatus incubates a small quantity of diluted whole blood with added solid or liquid reagents at body temperature, and mixes the blood via rocking and rotational motions so as to expose the blood uniformly to the reagents. The optical end-point detectors then measure the activity of platelets within the blood specimen, clotting time, and the clotting cascade. Several intermediate measurements are also available.


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