The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 1998

Filed:

Mar. 30, 1994
Applicant:
Inventors:

Thomas R Thieme, Independence, OR (US);

B Melina Cimler, Portland, OR (US);

Nanette M Klimkow, Beaverton, OR (US);

Assignee:

Epitope, Inc., Beaverton, OR (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ; G01N / ; A61B / ;
U.S. Cl.
CPC ...
435 22 ; 435-4 ; 435 29 ; 435805 ; 435810 ; 436 63 ; 422 56 ; 422 58 ; 422 61 ; 422102 ; 128760 ; 128762 ; 128769 ; 128771 ;
Abstract

An improved method for determining the presence of an analyte in an oral fluid sample. A portion of the sample is mixed or contacted with a chromogenic substrate effective to produce a colored product upon reaction with .alpha.-amylase present in the sample. After a selected reaction time, the reaction mixture is inspected to determine the level of such colored product produced. Production of a level of colored product above a selected threshold within the reaction time indicates that an effective volume of undiluted oral fluid sample has been collected which is sufficient to allow detection of the analyte. A device for use in the method is also disclosed.


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