The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 1998
Filed:
Feb. 02, 1996
Lloyd J Old, New York, NY (US);
Sydney Welt, New York, NY (US);
Gerd Ritter, New York, NY (US);
Richard J Simpson, Victoria, AU;
Edouard Nice, Victoria, AU;
R L Moritz, Victoria, AU;
B Catimel, Victoria, AU;
Hong Ji, Victoria, AU;
Anthony W Burgess, Victoria, AU;
Joan K Heath, Victoria, AU;
Sara J White, Victoria, AU;
Cameron Johnstone, Victoria, AU;
Ludwig Institute for Cancer Research, New York, NY (US);
Abstract
This invention relates to isolated protein and to peptides which are found on the surface of colon cells and colon cancer cells, as well as to nucleic acid molecules encoding said protein and peptides. The protein and peptides bind to tumor-associated antibodies, such as mAb A33. The monomeric protein has a molecular weight of about 43 kD as determined by SDS gel electrophoresis under non-reducing conditions. In addition, this invention relates to the use of said nucleic acid molecules, protein, in monomeric or multimeric form, and to antibodies to said peptides in diagnostic, screening and therapeutic methods. This invention further relates to antibodies specific for said protein, in monomeric or multimeric form, and to antibodies to said peptides.