The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 1998
Filed:
Apr. 03, 1996
Applicant:
Inventors:
Neil Roy Curtis, Puckeridge, GB;
Janusz Jozef Kulagowski, Bishops Stortford, GB;
Paul David Leeson, Monmouth Junction, NJ (US);
Mark Peter Ridgill, Watton-At-Stone, GB;
Assignee:
Merck, Sharp & Dohme, Ltd., Hoddesdon, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514300 ; 514253 ; 514256 ; 514269 ; 514272 ; 514274 ; 544232 ; 544238 ; 544310 ; 544315 ; 544319 ; 544324 ; 544328 ; 544331 ; 544333 ; 544405 ; 546113 ;
Abstract
A class of pyrrolo�2,3 -b!pyridine derivatives, linked via the 3-position thereof by a methylene group to a tetrahydropyridinyl moiety, the latter moiety being substituted in turn by an aryl- or heteroaryl-substituted divalent monocyclic radical, are ligands for dopamine receptorsubtypes within the body, in particular the D.sub.4 subtype, and are accordingly of use in the treatment and/or prevention of disorders of the dopamine system, including schizophrenia and depression.