The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 1998
Filed:
Oct. 06, 1995
Applicant:
Inventors:
Melvin E Klegerman, Chicago, IL (US);
Michael J Groves, Deerfield, IL (US);
Ronghua Wang, Hinsdale, IL (US);
Assignee:
Board of Trustees of The University of Illinois, Urbana, IL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; A61K / ; A61K / ; C12N / ;
U.S. Cl.
CPC ...
435 72 ; 4242341 ; 4242481 ; 435863 ; 514 23 ; 514 54 ; 536123 ; 5361231 ;
Abstract
A purified hot-water extract from Mycobacterium bovis (BCG vaccine) has been found to have significant antitumor activity against a mouse bladder tumor model and a murine sarcoma in vivo, but not in vitro. The material, termed PS1A1, has an approximate molecular weight of between 60 and 90 kDa, is freely soluble in water, but has low solubility in acetone or ethanol, and is remarkably heat-stable.