The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 1998
Filed:
Apr. 16, 1996
Zenta Tsuchihashi, Menlo Park, CA (US);
Andreas Gnirke, San Carlos, CA (US);
Winston J Thomas, San Mateo, CA (US);
Dennis T Drayna, San Mateo, CA (US);
David Ruddy, San Francisco, CA (US);
Roger K Wolff, Belmont, CA (US);
John N Feder, San Callos, CA (US);
Mercator Genetics, Menlo Park, CA (US);
Abstract
A single base-pair polymorphism involving a mutation from Guanine (G), in individuals unaffected by the hereditary hemochromatosis (HH) gene defect, to Adeninc (A), in individuals affected by the HH gene defect is disclosed. The presence or absence of the polymorphic allele is highly predictive of whether an individual is at risk from HH: the polymorphism is present in 82% of affected individuals and only 4% of a random population screen. Methods of diagnosis, markers, and primers are disclosed and claimed in accordance with the present invention.