The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 13, 1998
Filed:
Dec. 21, 1994
Applicant:
Inventors:
Donald B Kohn, Tarzana, CA (US);
Pia M Challita, Sherman Oaks, CA (US);
Assignee:
Other;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435325 ; 4353201 ; 4352351 ; 4351723 ; 435352 ; 435354 ; 536 241 ; 536 231 ; 424 931 ; 424 932 ; 424 9321 ; 514 44 ; 935 22 ; 935 32 ; 935 66 ; 935 70 ;
Abstract
Retroviral plasmid vectors which include an enhancer region obtained from a virus selected from the group consisting of Myeloproliferative Sarcoma Virus and polyoma virus, and a primer binding site obtained from murine retrovirus. The retroviral plasmid vector does not include a negative control region. The vector also may include a nucleic acid sequence which encodes demethylation of cytosine residues in the proviral LTR. Such plasmid vectors are especially useful in the generation of retroviral vector particles which may be expressed in embryonic cells, such as embryonic stem cells.