The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 13, 1998

Filed:

Jan. 19, 1995
Applicant:
Inventors:

John L Toner, Downingtown, PA (US);

David A Hilborn, Henrietta, NY (US);

Bruce J Murray, Walworth, NY (US);

Timothy Z Hossain, Ithaca, NY (US);

Robert A Snow, West Chester, PA (US);

Ashis K Saha, Frazer, PA (US);

Richard Philion, Averill Park, NY (US);

Clyde W Shearman, West Chester, PA (US);

Chandra Shah, Malvern, PA (US);

Assignee:

Nycomed Imaging AS, Oslo, NO;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07F / ; C07D / ;
U.S. Cl.
CPC ...
424-141 ; 424-153 ; 424-157 ; 424-165 ; 424-169 ; 424-173 ; 534 10 ; 534 14 ; 5303915 ; 5303917 ; 546256 ; 546257 ;
Abstract

The invention provides targeting radioactive immunoreagents comprising a metal radionuclide ion, a complexing agent having structure A-I, as defined in the specification, and an immunoreactive group covalently bonded to the complexing agent. The present invention also provides novel complexing agents having the structure A-I, as defined in the specification. The targeting radioactive immunoreagents are particularly useful in therapeutic and diagnostic imaging compositions and methods.


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