The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 1998

Filed:

Aug. 14, 1996
Applicant:
Inventors:

Edgar B Cahoon, Shoreham, NY (US);

John Shanklin, Shoreham, NY (US);

Ylva Lindgvist, Jarfalla, SE;

Gunter Schneider, Jarfalla, SE;

Assignee:

Associated Universities, Inc., Washington, DC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435419 ; 4351723 ; 435189 ; 4352401 ; 4352402 ; 4352404 ; 435243 ; 4352523 ; 43525411 ; 4352551 ; 4353201 ; 536 232 ;
Abstract

Disclosed is a methods for modifying the chain length and double bond positional specificities of a soluble plant fatty acid desaturase. More specifically, the method involves modifying amino acid contact residues in the substrate binding channel of the soluble fatty acid desaturase which contact the fatty acid. Specifically disclosed is the modification of an acyl-ACP desaturase. Amino acid contact residues which lie within the substrate binding channel are identified, and subsequently replaced with different residues to effect the modification of activity.


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