The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 1998
Filed:
Nov. 18, 1994
Applicant:
Inventors:
Abdel Karim Braham, Saint Denis, FR;
Pierre Smets, Villennes sur Seine, FR;
Rene Zalisz, Menucourt, FR;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C07H / ; C12Q / ; A61K / ;
U.S. Cl.
CPC ...
435375 ; 435-6 ; 536 245 ; 536 231 ; 536 243 ; 536 2432 ; 536 2433 ; 536 2531 ; 536 2534 ;
Abstract
A sequence of anti-direction, anti-messenger RNA oligonucleotides of .alpha.-TNF characterized in that it possesses the structure of the formula ##STR1## wherein X is hydrogen, or a sequence of 1 to 17 oligonucleotides in free form, in alkylated form, in sulfurated form or in the form of a poly L-lysine derivative useful for stopping the production of .alpha.-TNF.