The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 1998
Filed:
Jun. 07, 1995
Yusuke Nakamura, Kanagawa, JP;
Mitsuru Emi, Tokyo, JP;
Cancer Institute, Tokyo, JP;
Eisai Co., Ltd., Tokyo, JP;
Abstract
The present invention provide a gene present in a commonly deleted region of a chromosome in breast and ovarian cancers and encoding a novel protein, the protein ('MDC protein') encoded by the gene and a method for the diagnosis of cancer by using an antibody combinable to the protein. A detailed genetic map of human chromosome 17 was constructed to analyze the chromosome in breast and ovarian cancer tissues, and a gene encoding a novel protein was cloned and its structure was determined. As a result of gene analysis using DNA probes derived from the gene, a gene mutation was confirmed in breast cancer tissues. Moreover, a transformant carrying a plasmid containing the gene was grown to obtain the MDC protein. Furthermore, a monoclonal antibody was prepared by using the protein as an antigen.