The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 30, 1997

Filed:

Jun. 06, 1995
Applicant:
Inventors:

Daniela Santoli, Bryn Mawr, PA (US);

Giovanni Rovera, Bryn Mawr, PA (US);

Alessandra Cesano, Philadelphia, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N / ; C12N / ; C12N / ; A61K / ;
U.S. Cl.
CPC ...
424 9371 ; 424 931 ; 424 932 ; 424 9321 ; 424 937 ; 424534 ; 435-2 ; 435366 ; 435372 ; 4353723 ; 514-2 ; 514-9 ; 514 10 ; 514885 ; 552577 ; 552576 ; 552581 ;
Abstract

The invention provides a modified human cytotoxic T cell line, which is characterized by dual activity in vitro and in vivo against malignant cells and virus-infected cells. Also provided are effective and safe methods for use of the modified cells in adoptive therapy of cancer and untreatable vital diseases in MHC-mismatched recipients, and in marrow purging to achieve complete eradication of residual tumor cells from marrows of patients with leukemia and other types of cancer. Also provided are effective and safe methods for use of the cytokine stimulated, irradiated TALL-104 cells in the manufacture of a veterinary composition for adoptive therapy of canine and feline malignancies.


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Santoli, Daniela. (1997). Modified cytotoxic tall cell line and compositions and methods for (U.S. Patent No. 5702702). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5702702

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