The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 1997
Filed:
Jun. 01, 1995
James M Ligon, Basel, CH;
Thomas Schupp, Mohlin, CH;
James Joseph Beck, Cary, NC (US);
Dwight Steven Hill, Cary, NC (US);
John Andrew Ryals, Durham, NC (US);
Stephen Ting Lam, Raleigh, NC (US);
Philip E Hammer, Cary, NC (US);
Scott Joseph Uknes, Apex, NC (US);
Novartis Finance Corporation, New York, NY (US);
Abstract
The present invention is directed to the production of an antipathogenic substance (APS) in a host via recombinant expression of the polypeptides needed to biologically synthesize the APS. Genes encoding polypeptides necessary to produce particular antipathogenic substances are provided, along with methods for identifying and isolating genes needed to recombinantly biosynthesize any desired APS. The cloned genes may be transformed and expressed in a desired host organisms to produce the APS according to the invention for a variety of purposes, including protecting the host from a pathogen, developing the host as a biocontrol agent, and producing large, uniform amounts of the APS.