The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 09, 1997

Filed:

Jun. 07, 1995
Applicant:
Inventors:

Heungsik Yoon, Daejeon, KR;

Nakyen Choy, Daejeon, KR;

Sung Chun Kim, Daejeon, KR;

Ho Il Choi, Daejeon, KR;

Young Chan Son, Daejeon, KR;

Chi Hyo Park, Daejeon, KR;

Kwang-Yul Moon, Daejeon, KR;

Wonhee Jung, Daejeon, KR;

Chung Ryeol Kim, Daejeon, KR;

Chang Sun Lee, Daejeon, KR;

Jong Sung Koh, Seoul, KR;

Sang Soo Kim, Daejeon, KR;

Assignee:

LG Chemical Limited, Seoul, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
514314 ; 514326 ; 514475 ; 530331 ;
Abstract

Novel cis-epoxide compounds of formula (I) are useful for treating or preventing diseases caused by HIV infection: ##STR1## wherein A, B, R.sub.1 to R.sub.4 and n have the same meanings as defined in the specification. The novel HIV protease inhibitor of the formula (I) has a specific structure to form a stable bonding with the enzyme active site, which entails a highly enhanced irreversible inhibition against HIV protease.


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