The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 02, 1997
Filed:
Dec. 19, 1995
Showa Sangyo Co., Ltd., , JP;
Abstract
This invention provides a process for preparation of trans-4-hydroxy-L-proline which comprises either culturing Xanthomonas maltophilia NA-62 (FERM BP-4479), Xanthomonas maltophilia JCM No.3807 (FERM BP-4474) or Xanthomonas sp. JCM No.3857 (FERM BP-4475) in a nutrient medium containing collagen or gelatin or a partial hydrolyzate of collagen or gelatin, or contacting culture cells of the above microorganism with collagen or gelatin or a partial hydrolyzate of collagen or gelatin in an aqueous medium, and recovering trans-4-hydroxy-L-proline formed; and a process for preparation of an amino acid mixture which comprises contacting culture cells, fractured cells before or after removal of the broken pieces of the cells, or a crude enzyme obtained by subjecting the fractured cells after removal of the broken pieces of the cells to salting-out or solvent precipitation, from Xanthomonas maltophilia NA-62 (FERM BP-4479), Xanthomonas maltophilia JCM No.3807 (FERM BP-4474) or Xanthomonas sp. JCM No.3857 (FERM BP-4475), with collagen or gelatin or a partial hydrolyzate of collagen or gelatin in an aqueous medium, and recovering the amino acid mixture formed. Trans-4-hydroxy-L-proline, and an amino acid mixture containing trans-4-hydroxy-L-proline and L-proline in a high concentration are efficiently produced by this invention.