The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 1997
Filed:
Jun. 26, 1995
Kiyofumi Ishikawa, Tokyo, JP;
Takehiro Fukami, Tokyo, JP;
Takashi Hayama, Tokyo, JP;
Kenji Niiyama, Tokyo, JP;
Toshio Nagase, Tokyo, JP;
Toshiaki Mase, Tokyo, JP;
Kagari Fujita, Tokyo, JP;
Masaki Ihara, Tokyo, JP;
Fumihiko Ikemoto, Tokyo, JP;
Mitsuo Yano, Tokyo, JP;
Banyu Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
The invention relates to compounds which are antagonists of endothelin, to processes for their preparation, and to their use as pharmaceuticals. The compounds of the invention are Useful in the treatment of hypertension, pulmonary hypertension, Reynaud's disease, myocardial infarction, angina pectoris, acute renal failure, cerebral infarction, cerebral vasospasm, arteriosclerosis, asthma, endotoxin shock, endotoxin-induced multiple organ failure or disseminated intravascular coagulation, and/or cyclosporin-induced renal failure or hypertension.