The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 1997
Filed:
Jul. 19, 1994
Applicant:
Inventors:
Quirico Branca, Basel, CH;
Werner Neidhart, Freiburg im Breisgau, DE;
Henri Ramuz, Birsfelden, CH;
Heinz Stadler, Rheinfelden, CH;
Wolfgang Wostl, Grenzach-Wyhlen, DE;
Assignee:
Hoffmann La Roche Inc., Nutley, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
544242 ; 514326 ; 514397 ; 514380 ; 514399 ; 514400 ; 514616 ; 514 18 ; 514 19 ; 514394 ; 5142315 ; 546138 ; 548215 ; 5483381 ; 5483391 ; 5483061 ;
Abstract
The compounds of the formula ##STR1## in the form of optically pure diastereomers, mixtures of diastereomers, diastereomeric racemates or mixtures of diastereomeric racemates as well as pharmaceutically usable salts thereof inhibit the activity of the natural enzyme renin and can accordingly be used in the form of pharmaceutical preparations in the control or prevention of high blood pressure and cardiac insufficiency.