The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 1997

Filed:

Jan. 19, 1996
Applicant:
Inventors:

Robert Stewart Frank, Pembroke Pines, FL (US);

James Lynn Wyatt, Plantation, FL (US);

Assignee:

Coulter International Corp., Miami, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
436 66 ; 436 63 ; 436149 ; 436150 ; 422 73 ; 422 8201 ; 422 8202 ; 435-2 ; 324 711 ;
Abstract

This invention is related to an apparatus and method to determine the hemoglobin concentration of individual red blood cells by measuring the radio frequency resistance (RF) and direct current (DC) resistance resulting during the flow of the cells through a measurement aperture. The hemoglobin concentration of the cell is determined using the ratio of these two resistances. This determination can be made using a focused flow cell and a non-focused flow cell. In addition, the determination can be made with red blood cells which are either in their native, deformable state or with red blood cells that have been isovolumetrically sphered.


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