The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 1997
Filed:
Dec. 28, 1995
Hun-Taeg Chung, Iri, KR;
Il-Yang Pharm. Co., Ltd., Seoul, KR;
Abstract
The present invention relates to an anti-sense oligodeoxynucleotide to mRNA for one of major fibrogenic cytokines, TGF-.beta., which is secreted in large quantities in wound portion and then stimulates the fibrinoid degeneration of the tissue. The anti-sense oligodeoxynucleotide according to the present invention is complementarily bound to mRNA of TGF-.beta. to inhibit the genetic expression thereof and thus can inhibit the scarring due to the production of fibrogenic cytokines and the fibrinoid degeneration at the wound portion to treat the wound portion so as to have an appearance substantially identical to the normal tissue. Accordingly, the present invention also relates to the use of anti-sense oligodeoxynucleotide to TGF-.beta. as a scarring inhibitor.