The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 1997
Filed:
Oct. 05, 1994
Paul Ashton, Boston, MA (US);
Thomas J Smith, Weston, MA (US);
Peter G Glavinos, Doylestown, PA (US);
John D Conklin, Jr, Lexington, KY (US);
Peter A Crooks, Lexington, KY (US);
Robert M Riggs, Birmingham, AL (US);
Tadeusz Cynkowski, Lexington, KY (US);
Grazyna Cynkowska, Lexington, KY (US);
University of Kentucky Research Foundation, Lexington, KY (US);
Abstract
Prodrugs containing an active drug molecule linked to a polyethylene glycol group, and a method of use thereof are described. Exemplary soluble ester prodrugs contain naproxen, triamcinolone acetonide, gancyclovir, taxol, cyclosporin, dideoxyinosine, trihydroxy steroids, and flurbiprofen molecules linked to polyethylene glycol (PEG) groups. Pharmaceutical compositions containing these prodrugs, and a method of using these esters for treating disease states or symptoms are also described.