The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 1997

Filed:

Jun. 07, 1996
Applicant:
Inventors:

Mark R Pope, Grayslake, IL (US);

Peter J Tarcha, Lake Villa, IL (US);

David R Mees, St. Louis, MO (US);

Mary K Joseph, Libertyville, IL (US);

Terry A Pry, Libertyville, IL (US);

C Brent Putman, Round Lake Beach, IL (US);

Daniel D Subotich, Morton Grove, IL (US);

Assignee:

Abbott Laboratories, Abbott Park, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; G01N / ; C12Q / ;
U.S. Cl.
CPC ...
436518 ; 436523 ; 436528 ; 436529 ; 436530 ; 436531 ; 436533 ; 436534 ; 436823 ; 436548 ; 436810 ; 435-4 ; 435-79 ; 435962 ; 435963 ;
Abstract

A method for increasing the binding activity of specific binding members bound to a solid phase material, e.g., a particle, that has been sterically stabilized. This increase in binding activity is brought about by degrading a steric stabilizer on the surface of the solid phase material. The method involves both immobilizing a specific binding member on the surface of a solid phase material and degrading a steric stabilizer on the surface of that solid phase material. In the preferred embodiment, the method involves the immobilization of a specific binding member on the surface of the sterically stabilized solid phase material, with subsequent degradation of the steric stabilizer.


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