The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 1997
Filed:
May. 05, 1995
Applicant:
Inventors:
Gennaro Ciliberto, Casalpalocco, IT;
Rocco Savino, Pomezia, IT;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C07H / ; C07K / ; A61K / ;
U.S. Cl.
CPC ...
435 6952 ; 435 695 ; 435 6951 ; 435243 ; 4352523 ; 4353201 ; 530351 ; 930141 ; 930142 ; 930140 ; 536 235 ; 536 2352 ; 424 852 ; 424 856 ;
Abstract
The present invention is drawn to mutant interleukin 6, which has the amino acid arginine in position 176, replacing serine in position 176 with wild-type interleukin 6. The mutant interleukin 6 of the present invention has greater biological activity than the wild-type protein. The present invention is further drawn to methods of making mutant interleukin 6, having arginine at position 176 and methods of using the same.