The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 1997
Filed:
Aug. 13, 1996
Applicant:
Inventors:
Anthony J Martinez, Hamilton Square, NJ (US);
Richard B Greenwald, Somerset, NJ (US);
Assignee:
Enzon, Inc., Piscataway, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08G / ; C08L / ; A61K / ;
U.S. Cl.
CPC ...
4241781 ; 4241791 ; 525 541 ; 525403 ; 525408 ; 530406 ; 530410 ; 560182 ; 514449 ; 549433 ; 549510 ;
Abstract
The present invention is directed to methods of preparing high purity polyalkylene oxide carboxylic acids. The methods include reacting a polyalkylene oxide such as polyethylene glycol with a t-butyl haloacetate in the presence of a base followed by treatment with an acid such as trifluoroacetic acid. The resultant polymer carboxylic acids are of sufficient purity so that expensive and time containing purification steps required for pharmaceutical grade polymers are avoided.