The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 1997
Filed:
Sep. 01, 1995
Joachim Gunther, Kaiserslautern, DE;
Bernhard Krause, Frankfurt, DE;
Gernot Mader, Kelkheim, DE;
Wolfgang Sittig, Hofheim, DE;
Klaus Itter, Frankfurt, DE;
Klaus-Jurgen Simon, Kelkheim, DE;
Hoechst Aktiengesellschaft, Frankfurt, DE;
Abstract
This invention relates to a low-pressure chromatography column 1 having a diameter of more than 30 cm, and essentially consisting of a vertical cylinder 13 having a base plate 12, a lower sintered disk 3 arranged above the base plate 12, an upper sintered disk 16 fastened to the underside of a lid designed as a mobile plunger 4, and having at least three controllable elements 5 for raising or lowering the plunger 4, which are connected to the plunger 4, equipped with sensors 6 electrically connected to a control unit 10 for determining the vertical position and horizontal placement of the plunger 4. With the aid of an optical observation device (e.g., endoscope), the plunger/gel material can be adjusted exactly over the entire positioning range of the plunger. The advantages of the invention include simple and rapid production of the packing and purer products than could be obtained without such packing. The low-pressure chromatography column according to the invention is particularly suitable for purifying insulin and precursors of insulin thereof.