The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 1997

Filed:

Mar. 08, 1995
Applicant:
Inventors:

Federico C Gaeta, La Jolla, CA (US);

Michael F Powell, San Francisco, CA (US);

Howard M Grey, La Jolla, CA (US);

Alessandro D Sette, La Jolla, CA (US);

Thomas S Arrhenius, San Diego, CA (US);

Assignees:

Cytel Corporation, San Diego, CA (US);

Sandoz Ltd., Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
514 14 ; 514 15 ; 514 13 ;
Abstract

Peptide compositions are provided which bind MHC molecules of interest and inhibit T cell activation. The peptide compositions of the present invention comprise various isosteres of naturally occurring amino acid sequences. Such compositions may be used to treat diseases associated with particular DR alleles, including autoimmune diseases such as rheumatoid arthritis.


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