The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 1997
Filed:
Sep. 26, 1995
Applicant:
Inventors:
Karl-Siegfried Boos, Gauting, DE;
Dietrich Seidel, Feldafing, DE;
Annette Trautwein, Hassloch, DE;
Gerold Morsch, Willinghausen, DE;
Assignee:
B. Braun Melsungen AG, Melsungen, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C07K / ; C07K / ; A61M / ;
U.S. Cl.
CPC ...
210723 ; 210650 ; 210651 ; 210660 ; 210669 ; 210724 ; 210725 ; 210729 ; 210730 ; 210749 ; 210767 ; 210782 ; 436177 ; 436178 ; 530412 ; 530414 ; 530415 ; 530416 ; 530417 ; 530418 ; 530419 ; 604-4 ; 604-5 ;
Abstract
Disclosed is a process to remove tumour necrosis factor .alpha. (TNF.alpha.) or/and bacterial lipopolysaccharides (LPS) from an aqueous liquid, in particular blood, blood plasma or serum, in an extracorporeal perfusion system after removing corpuscular blood components if necessary, wherein (a) the pH value of the body fluid is adjusted to pH<6, (b) a precipitation reagent in the form of a polyanion is added, (c) precipitated substances are removed by filtration or/and centrifugation and (d) the resulting liquid is passed over an anion exchanger.